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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FOXD4 All Species: 9.7
Human Site: S16 Identified Species: 21.33
UniProt: Q12950 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12950 NP_997188.2 439 47251 S16 L R S T P Q R S L R D S D G E
Chimpanzee Pan troglodytes NP_001009014 413 45421 S16 L R S T P Q R S L R D S D G E
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q60688 444 48029 S16 L R S T P P P S P L S S D Q D
Rat Rattus norvegicus Q63245 101 11924
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516678 728 77542 Q149 R G E Q Q Q Q Q L R G S D G E
Chicken Gallus gallus P79772 394 40977 T14 G S D M S G Q T A L A A E D V
Frog Xenopus laevis Q9DEN4 371 40000 A9 T L S G S G S A S D M S G Q T
Zebra Danio Brachydanio rerio NP_571365 371 40457 A9 T L S G G T S A S N M S G Q T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q02361 456 49036 S14 P M H T L H D S V S L S P P L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_496411 333 37274
Sea Urchin Strong. purpuratus XP_001188749 401 43606 N13 T D L M E G I N I R P A N E Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.6 N.A. N.A. N.A. 48.6 20.5 N.A. 33 38.2 34.8 32.7 N.A. 30.9 N.A. 31.2 34.8
Protein Similarity: 100 83.1 N.A. N.A. N.A. 55.6 21.6 N.A. 41.4 46.7 46.4 45.3 N.A. 44 N.A. 43.2 44.8
P-Site Identity: 100 100 N.A. N.A. N.A. 53.3 0 N.A. 46.6 0 13.3 13.3 N.A. 20 N.A. 0 6.6
P-Site Similarity: 100 100 N.A. N.A. N.A. 60 0 N.A. 53.3 26.6 20 20 N.A. 26.6 N.A. 0 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 19 10 0 10 19 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 10 0 0 0 10 0 0 10 19 0 37 10 10 % D
% Glu: 0 0 10 0 10 0 0 0 0 0 0 0 10 10 28 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 0 19 10 28 0 0 0 0 10 0 19 28 0 % G
% His: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 10 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 28 19 10 0 10 0 0 0 28 19 10 0 0 0 10 % L
% Met: 0 10 0 19 0 0 0 0 0 0 19 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 10 0 0 10 0 0 % N
% Pro: 10 0 0 0 28 10 10 0 10 0 10 0 10 10 0 % P
% Gln: 0 0 0 10 10 28 19 10 0 0 0 0 0 28 10 % Q
% Arg: 10 28 0 0 0 0 19 0 0 37 0 0 0 0 0 % R
% Ser: 0 10 46 0 19 0 19 37 19 10 10 64 0 0 0 % S
% Thr: 28 0 0 37 0 10 0 10 0 0 0 0 0 0 19 % T
% Val: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _